[4O09m-2] 神経免疫と生体リズム

[4O09m-2-1] ミクログリアは免疫チェックポイント分子 Tim3を介してアミロイドβ病理を制御する

*木村 公俊^1,2,3,4、Ayshwarya Subramanian^1,2,3,5、Zhuoran Yin^1,2,3,6、Ahad Khalilnezhad^1,2,3,5、Yufan Wu^1,2,3,5、Danyang He^1,2,3、Dennis Selkoe^1,2,3、Aviv Regev⁵、Mario Suvà^5,7、Oleg Butovsky^1,2,3、Vijay Kuchroo^1,2,3,5 (1. The Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Mass General Hospital and Harvard Medical School, Boston, MA, USA.、2. Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.、3. Department of Neurology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA.、4. 京都大学大学院医学研究科　臨床神経学、5. Broad Institute of MIT and Harvard, Cambridge, MA, USA.、6. Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.、7. Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.)

キーワード：

microglia、Tim3、Alzheimer's disease、MGnD

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