[S07] Symposium 07 Physical and Metabolic Perspectives on Development, Growth and Diseases

10:32 AM - 10:44 AM JST(1:32 AM - 1:44 AM UTC)

[S07-04] A DLX5 distal enhancer is a skeleton specific cis-regulatory element involved in bone homeostasis and osteoporosisあるDLX5遠位エンハンサーは骨代謝や骨粗鬆症に関わる骨格特異的なシス制御エレメントである

*Shinse Fujita^1,2,6, Shoichiro Tani³, Harumi Nakao⁴, Yasuhide Iwanaga^1,2,6, Hiroyuki Okada^1,2, Shinsuke Ohba⁵, Taku Saito², Sakae Tanaka², Ung-il Chung^1,6, Hironori Hojo⁷ (1. Laboratory of Clinical Biotechnology, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 2. Department of Orthopaedic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 3. Children’s Medical Center Research Institute at the University of Texas Southwestern, Dallas, TX, USA, 4. Laboratory of Animal Resources, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan, 5. Department of Tissue and Developmental Biology, Graduate School of Dentistry, The University of Osaka , Osaka, Japan, 6. Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan, 7. Bioinformatics Research Unit, Graduate School of Dentistry, The University of Osaka, Osaka, Japan)

Keywords:

Bone metabolism,Bone development,Enhancer,Single-cell multiome,Genome-wide association study