講演情報
[S-16-2]Computational models toward novel biological mechanisms of tau spread in Alzheimer's disease
Jacob W. Vogel (Department of Clinical Science Malmö, SciLifeLab, Lund University)
Dr. Jacob Vogel is an Assistant Professor at Department of Clinical Sciences Malmö, SciLifeLab, Lund University (Sweden), supported by the SciLifeLab & Wallenberg National Program for Data-Driven Life Science. Dr. Vogel’s training involved a PhD at McGill University with Dr. Alan Evans, and a postdoctoral fellowship at the University of Pennsylvania with Dr. Theodore Satterthwaite.
Dr. Vogel applies computational and statistical modeling approaches to human imaging and multiomic data to better understand the genesis and progression of neurodegenerative diseases. A major focus of Dr. Vogel’s work involves characterization of individual differences in disease expression. Dr. Vogel also has a keen interest in understanding what factors contribute to selective vulnerability (or resilience) of brain tissue to certain pathologies. Many of these research pursuits are achieved through the wrangling, aggregation and fusion of large datasets, with a focus on reproducibility and synthesis of complementary information. Dr. Vogel is best known for his work describing the distribution and spread of tau pathology in Alzhiemer's disease, and how these phenomena vary across the Alzheimer's disease population.
Dr. Vogel applies computational and statistical modeling approaches to human imaging and multiomic data to better understand the genesis and progression of neurodegenerative diseases. A major focus of Dr. Vogel’s work involves characterization of individual differences in disease expression. Dr. Vogel also has a keen interest in understanding what factors contribute to selective vulnerability (or resilience) of brain tissue to certain pathologies. Many of these research pursuits are achieved through the wrangling, aggregation and fusion of large datasets, with a focus on reproducibility and synthesis of complementary information. Dr. Vogel is best known for his work describing the distribution and spread of tau pathology in Alzhiemer's disease, and how these phenomena vary across the Alzheimer's disease population.