Oral Presentation 04-1 "Metabolism & Disease Models"

10:15 AM - 10:30 AM JST(1:15 AM - 1:30 AM UTC)

[OP04-1-02] Endogenous chondroitin extends the lifespan and healthspan by repressing the formation of tubular lysosome in C. elegans 内在性コンドロイチンは、チューブ状リソソームの形成抑制によって寿命と健康寿命を伸長する

*Yukimasa Shibata¹, Yuri Tanaka¹, Hiroyuki Sasakura², Yuki Morioka², Toshihiro Sassa³, Shion Fujii¹, Kaito Mitsuzumi¹, Masashi Ikeno², Yukihiko Kubota⁴, Kenji Kimura¹, Hidenao Toyoda⁵, Kosei Takeuchi², Kiyoji Nishiwaki¹ (1. Kwansei Gakuin University, Department of Biomedical Sciences, School of Biological and Enviromental Sciences, 2. Aichi Medical University,Department of Medical Cell Biology, School of Medicine, 3. RIKEN Center for Developmental Biology, 4. Ritsumeikan University, Department of Bioinformatics, College of Life Sciences, 5. Ritsumeikan University, Laboratory of Bio-analytical Chemistry, College of Pharmaceutical Sciences)

Keywords:

Aging,Chondroitin,Lysosome,ECM,C. elegans,lifespan,healthspan,V-ATPase

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