Session Details
Oral Presentation 04-1 "Metabolism & Disease Models"
Thu. Jun 20, 2024 10:00 AM - 11:15 AM JST
Thu. Jun 20, 2024 1:00 AM - 2:15 AM UTC
Thu. Jun 20, 2024 1:00 AM - 2:15 AM UTC
Room E(Miyako Messe(B1F)/Meeting Room)
Chairpersons:Kazuhide Asakawa(NIG), Hina Kosakamoto(RIKEN BDR)
[OP04-1-01]Postnatal alterations in cardiac purine metabolism cause cardiomyocyte cell cycle arrest出生後の心臓におけるプリン代謝の変化は心筋増殖の停止を引き起こす
*Yuichi Saito1, Yuki Sugiura2, Tai Sada1, Akane Sakaguchi1, Mari Kaneko1, Hiroshi Kiyonari1, Wataru Kimura1 (1. RIKEN BDR, 2. Univ. of Kyoto)
[OP04-1-02]Endogenous chondroitin extends the lifespan and healthspan by repressing the formation of tubular lysosome in C. elegans 内在性コンドロイチンは、チューブ状リソソームの形成抑制によって寿命と健康寿命を伸長する
*Yukimasa Shibata1, Yuri Tanaka1, Hiroyuki Sasakura2, Yuki Morioka2, Toshihiro Sassa3, Shion Fujii1, Kaito Mitsuzumi1, Masashi Ikeno2, Yukihiko Kubota4, Kenji Kimura1, Hidenao Toyoda5, Kosei Takeuchi2, Kiyoji Nishiwaki1 (1. Kwansei Gakuin University, Department of Biomedical Sciences, School of Biological and Enviromental Sciences, 2. Aichi Medical University,Department of Medical Cell Biology, School of Medicine, 3. RIKEN Center for Developmental Biology, 4. Ritsumeikan University, Department of Bioinformatics, College of Life Sciences, 5. Ritsumeikan University, Laboratory of Bio-analytical Chemistry, College of Pharmaceutical Sciences)
[OP04-1-03]Cell size-dependent metabolic disparities are exaggerated among the spinal motor neurons of zebrafish ALS model細胞サイズに依存した運動ニューロンのエネルギー代謝格差とALS病態
*Kazuhide Asakawa1,2, Hiroshi Handa3, Koichi Kawakami1,2 (1. National Institute of Genetics, 2. SOKENDAI, 3. Tokyo Medical University)
[OP04-1-04]Epigenetic control by Polyhomeotic Homolog 1 (Phc1) in the Nervous System Developmentクロマチン構造と脳発生の関係を明らかにする目的で、ポリコーム型転写抑制複合体に着目する。この構成因子の1つPhc1は、変異ES細胞は神経の初期発生に異常を示す一方、マウス変異胚は小頭症となる。
*Noriaki Sasai1, Agnes Lee Chen Ong1, Manabu Shirai2, Takuma Shinozuka1, Toshiya Kokaji1 (1. Nara Institute of Science and Technology, 2. Omics Research Center, National Cerebral and Cardiovascular Center))
[OP04-1-05]A point mutation in SBNO1 gene found in an autistic patient affects the protein function in the cortical neurons causing autism-related phenotypes
*Sunjidmaa Zolzaya1, Dai Ihara1, Hidenori Tabata2, Hayato Naka-Kaneda1, Kimi Araki4, Alberto Fernández Jaén3, Yu Katsuyama1 (1. Shiga University of Medical Science, 2. Aichi Developmental Disability Center, 3. Universidad Europea de Madrid , 4. Kumamoto university)