[OP10] OP10 Proliferation and Differentiation

10:37 AM - 10:49 AM JST(1:37 AM - 1:49 AM UTC)

[OP10-2] Long-term expansion of basal cells and the novel differentiation methods identify mechanisms for switching Claudin expression in normal epithelia

*Akihito Inoko¹, Norihito Soga^1,2, Minako Suzuki¹, Tohru Kiyono³, Junichi Ikenouchi⁴, Takahiro Kojima², Yoshikatsu Sato⁵, Daisuke Saito⁴, Tatsuo Miyamoto⁶, Naoki Goshima⁷, Hideaki Ito¹, Kenji Kasai¹ (1. Department of Pathology, Aichi Medical University Shool of Medicine, 2. Department of Urology, Aichi Cancer Center Hospital, 3. Project for Prevention of HPV-Related Cancer, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 4. Department of Biology, Faculty of Sciences, Kyushu University, 5. Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, 6. Department of Molecular and Cellular Physiology, Yamaguchi University Graduate School of Medicine, 7. Molecular Profiling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST))

Keywords:

Cell differentiation,Claudin,Epithelial-mesenchymal transition (EMT),Primary cell culture,Basal cell

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