Session Details
[SWS01]Nuclear Pore Complex and Chromatin: Gatekeepers of Genome Regulation[E]
Tue. Jul 15, 2025 4:45 PM - 6:00 PM JST
Tue. Jul 15, 2025 7:45 AM - 9:00 AM UTC
Tue. Jul 15, 2025 7:45 AM - 9:00 AM UTC
Room B(5F Small Hall1)
Chairpersons:Richard Wong(Kanazawa Univ.), Yuki Okada(Univ. of Tokyo)
Co-hosted by:Grant-in-Aid for Transformative Research Areas, Genome Modality
This workshop will focus on the nuclear pore complex (NPC), a structure that bridges the nucleus and cytoplasm, as well as its components, known as nucleoporins, and the additional role of chromatin in cellular function. The NPC is a massive molecular assembly formed by approximately 1,000 copies of about 30 different types of nucleoporins. It serves as a small pore in the nuclear envelope, facilitating the transport of essential biomolecules, including proteins, RNA, and even chromatin-associated molecules, between the nucleus and cytoplasm. Recent studies have revealed that the NPC is a highly dynamic and functional structure, whose architecture and activity can change in response to various factors such as cellular development, differentiation, and environmental conditions. This workshop aims to provide an open forum for discussing recent insights and breakthroughs in NPC and nucleoporin research, as well as the emerging understanding of how these structures interact with chromatin.
This workshop will focus on the nuclear pore complex (NPC), a structure that bridges the nucleus and cytoplasm, as well as its components, known as nucleoporins, and the additional role of chromatin in cellular function. The NPC is a massive molecular assembly formed by approximately 1,000 copies of about 30 different types of nucleoporins. It serves as a small pore in the nuclear envelope, facilitating the transport of essential biomolecules, including proteins, RNA, and even chromatin-associated molecules, between the nucleus and cytoplasm. Recent studies have revealed that the NPC is a highly dynamic and functional structure, whose architecture and activity can change in response to various factors such as cellular development, differentiation, and environmental conditions. This workshop aims to provide an open forum for discussing recent insights and breakthroughs in NPC and nucleoporin research, as well as the emerging understanding of how these structures interact with chromatin.
[SWS01-01]Nano Imaging in Nuclear Pore Territories
*Richard Wong1 (1. WPI-NanoLSI, Kanazawa University)
[SWS01-02]Role of Nup132 at meiotic centromeres in fission yeast with unique NPC structure
Haruhiko Asakawa1, Hui-Ju Yang2, Tatsuo Fukagawa1, Yasushi Hiraoka1, *Haraguchi Tokuko1 (1. Osaka University, 2. National Health Research Institutes, Taiwan)
[SWS01-03]RNA Export Mechanisms and Viral Strategies
*Ichiro Taniguchi1 (1. Osaka Univ. Graduate School of Frontier Biosciences)
[SWS01-04]Role of nucleoporin fusion proteins in the regulation of gene expression
*Masahiro Oka1 (1. Osaka Univ. Research Institute of Microbial Diseases)
[SWS01-05]Structural Diversity and Functional Roles of Nuclear Transport Pathways
*Naoko Imamoto1, Makoto Kimura2 (1. Graduate School of Medical Safety Management, Jikei University of Health Care Sciences, 2. Molecular Physiology Laboratory, RIKEN Pioneering Research Institute)