Session Details
[WS06]The Blueprint of Complex and Functional Intracellular Structures[J]
Thu. Jul 17, 2025 9:00 AM - 10:15 AM JST
Thu. Jul 17, 2025 12:00 AM - 1:15 AM UTC
Thu. Jul 17, 2025 12:00 AM - 1:15 AM UTC
Room A(2F Large Hall)
Chairpersons:Daiju Kitagawa(Univ. of Tokyo), Toshiyuki Oda(Yamanashi Univ.)
Co-hosted by:Grant-in-Aid for Transformative Research Areas (A) : Cluster Cell Biology
Within cellular environments, biomolecules engage in self-organization processes, leading to the formation of highly structured entities that are crucial for various biological functions. This intricate process is not solely driven by intermolecular interactions but is also significantly influenced by spatial constraints imposed by molecular crowding and specific platform effects within the cellular microenvironment. The resulting supramolecular complexes exhibit distinct volumes and physical robustness, operating as finely tuned machineries. This workshop aims to present recent advancements in the realm of "biological cluster" research, with a specific focus on endeavors to bridge the disparity between structural data on protein complexes and their functional assemblies within cells.
Within cellular environments, biomolecules engage in self-organization processes, leading to the formation of highly structured entities that are crucial for various biological functions. This intricate process is not solely driven by intermolecular interactions but is also significantly influenced by spatial constraints imposed by molecular crowding and specific platform effects within the cellular microenvironment. The resulting supramolecular complexes exhibit distinct volumes and physical robustness, operating as finely tuned machineries. This workshop aims to present recent advancements in the realm of "biological cluster" research, with a specific focus on endeavors to bridge the disparity between structural data on protein complexes and their functional assemblies within cells.
[WS06-01]Scaffold-dependent mechanisms of centriole assembly
*Daiju Kitagawa1, Kasuga Takumi1, Shoji Hata1 (1. Tokyo University, Graduate School of Pharmaceutical Sciences)
[WS06-02]Biochemical properties and molecular dynamics of the chromosome-weaving SMC complex
*Murayama Yasuto1, Kurokawa Yumiko1 (1. National Institute of Genetics)
[WS06-03]Structural analysis of sacromeregenesis in cardiomyocytes using cryo-electron tomography
*Toshiyuki Oda1, Hideyuki Miyazawa1, Harumi Arai1 (1. University of Yamanashi)