Joint Meeting of JSCB 77th and JSDB 58th
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Session Details

Symposium

[S07]Reconstructing functional nuclei -Nuclei in early embryos -[E]

Thu. Jul 17, 2025 1:10 PM - 3:10 PM JST
Thu. Jul 17, 2025 4:10 AM - 6:10 AM UTC
Room F(9F Conference Room903)
Chairpersons:Tokuko Haraguchi(Osaka Univ.), Kazuo Yamagata(Kindai Univ.)
The cell nucleus of a fertilized egg contains all the genetic information required to become that organism. Information about the DNA sequences and proteins that shape life has been accumulated. Based on this information, an approach to reconstruct functional cell nuclei has been taken, making it possible to investigate previously unexplained physical quantities such as time elements, spatial elements, quantity, and length. This workshop will introduce research attempting to reconstruct nuclear functions in fertilized eggs and early embryos.
1:10 PM - 1:15 PM JST(4:10 AM - 4:15 AM UTC)

Opening Remarks

1:15 PM - 1:38 PM JST(4:15 AM - 4:38 AM UTC)

[S07-02]Rapid pronucleus assembly using cytoplasmic RNAs in fertilized eggs of Xenopus laevis

Mizuki Ikeda1, Yuto Tanaka1, Tatsuya Shohoji1, *Yuki Hara1 (1. Yamaguchi Univ., Faculty of Science)
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1:38 PM - 2:01 PM JST(4:38 AM - 5:01 AM UTC)

[S07-03]How DNA chains choose their place: Entropic and enthalpic sorting in artificial nuclei

*Miho Yanagisawa1 (1. Univ. Tokyo, Komaba Inst. Sci.)
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2:01 PM - 2:24 PM JST(5:01 AM - 5:24 AM UTC)

[S07-04]Deciphering chromosome behavior in early mouse embryos through DNA replication dynamics

*Ichiro Hiratani1 (1. RIKEN Center for Biosystems Dynamics Research (RIKEN BDR))
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2:24 PM - 2:47 PM JST(5:24 AM - 5:47 AM UTC)

[S07-05]Designing functional artificial kinetochores and their applications in eggs

*Tomoya Kitajima1 (1. RIKEN Center for Biosystems Dynamics Research)
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2:47 PM - 3:10 PM JST(5:47 AM - 6:10 AM UTC)

[S07-06]Conditions for Nuclear Formation Revealed by Reconstitution of Artificial Nucleus in Mouse Eggs.

*Kazuo Yamagata1 (1. Kindai University, FACULTY OF BIOLOGY-ORIENTED SCIENCE AND TECHNOLOGY)
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