Joint Meeting of JSCB 77th and JSDB 58th
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Session Details

Symposium

[S08]Molecular mechanisms underpinning diverse physiological functions of autophagy[E]

Fri. Jul 18, 2025 9:00 AM - 11:00 AM JST
Fri. Jul 18, 2025 12:00 AM - 2:00 AM UTC
Room A(2F Large Hall)
Chairpersons:Hitoshi Nakatogawa(Science Tokyo), Ikuko Koyama-Honda(Univ. of Tokyo)
Autophagy is a conserved cellular degradation system essential for maintaining cellular and organismal homeostasis. In recent years, the field has advanced rapidly, uncovering new physiological roles for autophagy. In this symposium, six leading scientists will present cutting-edge research that deepens our insights into the molecular basis of the diverse functions of autophagy, including stress adaptation, lysosomal maintenance, immune regulation, neurodevelopment, neuroprotection, and plant seed development.
9:00 AM - 9:20 AM JST(12:00 AM - 12:20 AM UTC)

[S08-01]Regulation of p62 condensates by atypical ubiquitination

*Jun-ichi Sakamaki1, Masaaki Komatsu1 (1. Juntendo Univ.)
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9:20 AM - 9:40 AM JST(12:20 AM - 12:40 AM UTC)

[S08-02]Functional analysis of the BCAS3-PHAF1 complex associated with human neurodevelopmental disease

*Waka Kojima1, Noriyuki Matsuda1, Naonobu Fujita2, Koji Yamano3,1 (1. Department of Biomolecular Pathogenesis, Institute of Science Tokyo, 2. Cell Biology Center, Institute of Science Tokyo, 3. Intracellular Quality Control Project, Tokyo Metropolitan Institute of Medical Science)
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9:40 AM - 10:00 AM JST(12:40 AM - 1:00 AM UTC)

[S08-03]The mechanism underlying lysosomal microautophagic degradation of STING

*Yoshihiko Kuchitsu1, Shoji Tsumugi, Kanako Sato, Ruri Shindo, Tomohiko Taguchi (1. Graduate School of Life Sciences, Tohoku University)
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10:00 AM - 10:20 AM JST(1:00 AM - 1:20 AM UTC)

[S08-04]Molecular mechanisms underlying lysosomal damage response mediated by ATG8s lipidation and the ESCRTs.

*AKIKO KUMA1, MARIKA SAEKI1, KEISUKE TABATA2, MAHO HAMASAKI1, HIDETAKA KOSAKO3, TAMOTSU YOSHIMORI1 (1. Osaka Univ., Grad. Sch. of Med., 2. Juntendo Univ, 3. Tokushima Univ.)
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10:20 AM - 10:40 AM JST(1:20 AM - 1:40 AM UTC)

[S08-05]Autophagy-mediated quality control of a photoreceptor during seed development in Arabidopsis

Keisuke Seta1, *Kohki Yoshimoto1 (1. Department of Life Sciences, School of Agriculture, Meiji University)
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10:40 AM - 11:00 AM JST(1:40 AM - 2:00 AM UTC)

[S08-06]Autophagy-Mediated Quality Control and Functional Recovery in the Nervous System

*Noboru Mizushima1, Tomoya Eguchi1, Yuki Kanda1 (1. The University of Tokyo, Graduate School of Medicine)
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