Session Details
[S09]Spatiotemporal Genomics in Development and Cell Biology[E]
Fri. Jul 18, 2025 9:00 AM - 11:00 AM JST
Fri. Jul 18, 2025 12:00 AM - 2:00 AM UTC
Fri. Jul 18, 2025 12:00 AM - 2:00 AM UTC
Room B(5F Small Hall1)
Chairpersons:Takuya Yamamoto(Kyoto Univ.), Yasuyuki Ohkawa(Kyushu Univ.)
Co-hosted by: JST-CREST, Multicellular Interaction
Precise gene regulation in time and space is fundamental to both developmental and cell biology, covering processes from genome organization to RNA output and cellular behavior. Recent advances in epigenomics and spatial transcriptomics have enabled us to explore this complexity with remarkable resolution. This symposium focuses on how DNA replication dynamics, chromatin modifications, enhancer landscapes, and spatial gene expression coordinate to shape cell fate, identity, and tissue architecture. This symposium features emerging young researchers driving the next generation of innovation in genomics, developmental biology, and cell biology. This symposium is co-organized with the JST CREST program "Multicellular Interaction", which promotes integrated approaches to spatiotemporal gene regulation and multicellular dynamics through quantitative understanding of multicellularity enabled by cutting-edge measurement and analytical technologies.
Precise gene regulation in time and space is fundamental to both developmental and cell biology, covering processes from genome organization to RNA output and cellular behavior. Recent advances in epigenomics and spatial transcriptomics have enabled us to explore this complexity with remarkable resolution. This symposium focuses on how DNA replication dynamics, chromatin modifications, enhancer landscapes, and spatial gene expression coordinate to shape cell fate, identity, and tissue architecture. This symposium features emerging young researchers driving the next generation of innovation in genomics, developmental biology, and cell biology. This symposium is co-organized with the JST CREST program "Multicellular Interaction", which promotes integrated approaches to spatiotemporal gene regulation and multicellular dynamics through quantitative understanding of multicellularity enabled by cutting-edge measurement and analytical technologies.
[S09-01]Embryo-specific regulation of DNA replication and 3D genome organization in mice
*Saori Takahashi1, Hirohisa Kyogoku1,2, Takuya Hayakawa3, Hisashi Miura1, Asami Oji1, Yoshiko Kondo1, Shin-ichiro Takebayashi3, Tomoya S. Kitajima1, Ichiro Hiratani1 (1. RIKEN, BDR, 2. Graduate School of Agricultural Science, Kobe University, 3. Graduate School of Bioresources, Mie University)
[S09-02]Decoding spatiotemporal dynamics of the tissue- and stage- specific enhancer formation by Polycomb repressive complexes
*Hiroki Sugishita1, Kazunori Hojo1, Yukiko Gotoh1,2 (1. Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2. International Research Center for Neurointelligence (WPI-IRCN), The University of Tokyo)
[S09-03]The functional role of the KMT2 (MLL) family in chromatin contacts and gene activation during embryonic stem cell differentiation
*Naoki Kubo1 (1. RIKEN BRC)
[S09-04]Transcriptomic Views of Developmental Biology
*Akiko Oguchi1,2, Raku Son1,2, Yasuhiro Murakawa1,2 (1. RIKEN Center for Integrative Medical Sciences, 2. Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University)
[S09-05]Transcriptional Clusters and Gene Locus Reorganization in Myogenic Differentiation
*Yuko Sato1, Takeru Fujii1, Kosuke Tomimatsu1, Hiroshi Kimura2, Yasuyuki Ohkawa1 (1. Kyushu University, MIB, 2. Institute of Science Tokyo, IIR)
[S09-06]Whole-mount in situ sequencing: scalable and cost-effective 3D spatial transcriptomics
*Kazunori Sunadome1,2, Takuya Yamamoto1,2 (1. Kyoto Univ. Advanced Study of Human Biology (ASHBi), 2. Kyoto Univ. Center for iPS Cell Research and Application (CiRA))